Nanomedicines represent a leap forward in healthcare, offering treatments that are more effective, personalizable, and with fewer side effects. However, their clinical development faces unique characterization, manufacturing and regulatory challenges due to their inherent complexity. Metrino, a vanguard European project, addresses them to streamline standardisation in nanomedicine, ensuring innovation aligns with standardisation.
Standardising Excellence: Our commitment to increase confidence in quality measurements of nanomedicines drives us to develop and harmonise SOPs (Standard Operating Procedures) and to make them available for the community. We create clear, authoritative guidelines that pave the way for consistent, high-quality research and new consensus standards in nanomedicine.
Charting the Future of Reference Materials: At Metrino, we're shaping a roadmap for the development of certified reference materials of LNPs, liposomes and metal oxide nanoparticles, in collaboration with industry leaders, to ensure they represent formulations on the market. Each reference material will have homogeneous and stable attributes — be it particle size, chemical composition, drug loading, etc. — setting new benchmarks for validating accurate measurement procedures in the nanomedicine field.
Creating a Collaborative Ecosystem: Metrino is more than just a project; it's the seed of a burgeoning community. We are dedicated to establishing a forum where metrology institutes, researchers, industry, and regulators can converge to exchange visions and solutions. This collaborative network is key to driving nanomedicine from the laboratory to the clinic, fostering an environment where ideas, expertise, and innovations in metrology can thrive.
The METRINO project is an ambitious European collaborative initiative funded by the European Partnership on Metrology, aiming to establish Europe as a leader in nanomedicine metrology.
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The METRINO project has received funding from the European Partnership on Metrology (Grant #22HLT04), co-financed from the European Union’s Horizon Europe Research and Innovation Programme and by the Participating States. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or EURAMET. Neither the European Union nor the granting authority can be held responsible for them.