WP1: Preparation of Reference Material candidates

Main goals:

1. Provide metal oxide and lipidic nanoparticle formulation to the technical workpackages for developing, and harmonising traceable methodologies and SOPs for measuring their regulatory-relevant  properties
2. Select at least three formulations as reference material candidates, perform initial stability and homogeneity studies, and define a roadmap for their production and commercialisation as reference materials

 

Nanoparticle formulations:

• Superparamagnetic FexOy NPs with core sizes < 10 nm and > 10 nm;
• HfO2 NPs with core sizes < 10 nm and > 10 nm;
• Fluorescent multi-element nanoparticles like NaGdxY1-xF4 doped with Yb(III) and Er(III)
• LNPs-mRNA and LNPs-siRNA
• Liposomes

 

WP1 Leader

Dr. rer. nat. Ute Resch-Genger
Head of Biophotonics

Short bio: Dr. Ute Resch-Genger is head of division Biophotonics at the Federal Institute for Materials Research and Testing (BAM). Her research interests include photophysics of molecular and nanocrystalline emitters, stimuli-responsive optical probes, signal enhancement, multiplexing, and encoding strategies, and nanometrology. She also develops concepts for the standardization and validation of optical-spectroscopic measurements including reference materials and standardizable methods for the quantification of surface functionalities on nanomaterials. In addition, she is involved in national and international standardization activities on optical measurements and the characterization of nanomaterials