Natural and pharmaceutical estrogens are key Endocrine Disrupting Chemicals (EDC) which are monitored differently depending on the country, and for which standardised reference methods are currently not available. The overall objective of the project is to develop reliable and harmonised measurement methods for estrogens, to comply with the Water Framework Directive requirements (Directive 2013/39EC, Commission Directive 2009/90/EC and Commission Implementation Decision (EU) 2018/840). The outcomes of this project, in particular the validated mass spectrometry-based reference methods, will be disseminated to CEN/ TC 230 and ISO/ TC 147 to be fed into the documentary standards they develop.
The overall objective of this project is to develop traceable measurement methods for endocrine disrupting chemicals, with a specific focus on three estrogens of the first Watch List (17βE2, 17αEE2, E1) satisfying the requirements of Directive 2013/39/EC, Directive 2009/90/EC and Commission implementation Decision (EU) 2018/840, hence improving the comparability and compatibility of measurement results within Europe.
Three National Metrology Institutes
Two Designated Institutes