The aim of this work package is to optimise MS-based detection methods for the analysis of 5 selected estrogenic chemicals in whole water samples at concentrations not exceeding 30 % of the EQS levels for 3 selected estrogens, and to improve the effect-based methods (EBM).
This work package aims to:

1. harmonise MS-based detection methods that have the potential to meet the requirements described in the Directive 2009/90/EC (QA/QC Directive) and watch list (WL) under the WFD;
2. test and optimise selected bioassays for the endocrine disrupting chemical (EDC) detection at EQS level;
3. compare the different MS-based methods either analytical or biological based methods and recommend the use to the regulatory agencies and other bodies engaged to measure EDC.

Moreover, this work package will develop traceable measurement methods for the determination of the targeted EDC and ensure their transfer to the normative standardisation bodies.

• Task 2.1: Purity assessment to ensure traceability of MS-based and Effect-based methods
• Task 2.2: Optimisation and evaluation of MS-based methods
• Task 2.3: Optimisation and evaluation of four selected effect-based methods
• Task 2.4: Comparison of optimised MS-based and effect-based methods and recommendations

WP leader: Paolo de Zorzi, ISPRA, contact: paolo.dezorzi@isprambiente.it